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A diterpene quinone from the bark of Cryptomeria japonica
Hisayoshi Kofujita1, Michikazu Ota, Kouetsu Takahashi
1Faculty of Agriculture, Iwate University, Ueda 3-18-8, Morioka 020-8550, Japan. kofujita@iwate-u.ac.jp
Phytochemistry
|November 28, 2002
Abstract:
A diterpene, cryptoquinone, was isolated from the bark of Cryptomeria japonica, the structure, 7,11,14-trioxoabieta-8,12-diene, was established by spectral analyses and X-ray crystallography. This diterpene quinone showed moderate antifungal activities against Pyricularia orizae and Alternaria alternata, and cytotoxic activity against mouse lymphoid neoplasm (P388) cells with an IC(50) of 0.26 microg/ml.