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Updated: Jul 29, 2026

Controlled Microfluidic Environment for Dynamic Investigation of Red Blood Cell Aggregation
Published on: June 4, 2015
The changes of low-shear-rate hemorheological properties depending on the fluid used for transfusion
Anna Marcinkowska-Gapińska1, Piotr Kowal, Zbigniew Chałupka
1Department of Neurology, Karol Marcinkowski University of Medical Sciences in Poznań, Przybyszewskiego 49, 60-355 Poznań, Poland. margap@poczta.onet.pl
Abstract:
We investigated the influence of kind of fluids used for transfusion - crystalloids and colloids - on the rheological parameters of blood with a special focus on the range of low shear rates. The blood viscosity measurements were performed with the use of a rotary-oscillatory rheometer Contraves LS 40. The investigation includes the measurements of blood viscosity and a hematocrit value at three stages: before, just after and two hours after transfusion. On the basis of results obtained for a group of patients prepared for procedures in epidural anaesthesia we concluded that the dilution effect for colloids (HES and dextran) was maintained longer then for crystalloids (Ringer solution). Measurements of blood viscosity at the shear rate of 1 s(-1) showed that this viscosity had the smallest value in the group of patients with HES 200/0.5 as a transfusion fluid (p<0.001).
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