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[Adipose tissue within peripheral nerves. Study of the human sciatic nerve].
M A Reina1, A López, J A De Andrés
1Servicio de Anestesiología y Reanimación del Hospital de Móstoles y del Hospital Montepríncipe, Madrid. miguelangel.rei@terra.es
Revista Espanola De Anestesiologia Y Reanimacion
|November 29, 2002
Summary
Intraneural adipose tissue surrounds nerve fascicles, forming sheaths that may impede local anesthetic diffusion. This distribution can affect the effectiveness of anesthetic blockade in the lower extremity.
Area of Science:
- Neuroanatomy
- Histology
Context:
- Peripheral nerve anatomy is crucial for regional anesthesia.
- Understanding intraneural structures aids in optimizing anesthetic techniques.
Purpose:
- To characterize the distribution of intraneural adipose cells relative to nerve fascicles.
- To investigate the anatomical basis for anesthetic blockade in the lower extremity.
Summary:
- Sciatic nerve samples revealed adipose tissue surrounding nerve fascicles, forming variable-thickness sheaths.
- Adipocytes, approximately 40 microns in diameter, were observed within the epineurium.
- This adipose tissue distribution may influence local anesthetic diffusion.
Impact:
- The findings suggest intraneural adipose tissue can create barriers affecting anesthetic spread.
- This anatomical insight may inform strategies to improve the success and predictability of lower extremity nerve blocks.