Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Human viral cardiomyopathy.

Bernhard Maisch1, Arsen D Ristic, Irene Portig

  • 1Department of Internal Medicine-Cardiology, Philipps-University Marburg, Germany. maisch@Mailer.Uni-Marburg.DE

Frontiers in Bioscience : a Journal and Virtual Library
|November 29, 2002
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Relevance of clinical ethics support services in specialized outpatient palliative care teams and inpatient hospices.

BMC palliative care·2026
Same author

Current state of knowledge on the epidemiology, aetiology, diagnosis, and management of heart involvement in eosinophilia. A Clinical Consensus Statement of the ESC Working Group on Myocardial & Pericardial Diseases.

European journal of heart failure·2026
Same author

[2025 ESC Guidelines-new and revised recommendations].

Herz·2026
Same author

[ESC guidelines on myocarditis and pericarditis : First combined European guidelines for myocarditis and pericarditis].

Herz·2026
Same author

[2025 ESC Guidelines for the management of myocarditis and pericarditis].

Giornale italiano di cardiologia (2006)·2025
Same author

Comparative analysis of full-length 16s ribosomal RNA gene sequencing in human oropharyngeal swabs using primer sets with different degrees of degeneracy.

Frontiers in cellular and infection microbiology·2025

Viral heart infections are common but usually resolve. Rarely, they cause viral cardiomyopathy, a dilated heart with persistent viruses, potentially leading to heart failure.

Area of Science:

  • Cardiology
  • Virology
  • Pathology

Background:

  • Viral heart infections are common, often asymptomatic, and self-resolving.
  • Rarely, these infections can cause significant cardiac damage, leading to viral cardiomyopathy and congestive heart failure.
  • Viral cardiomyopathy is characterized by persistent viruses within a dilated heart, sometimes with myocardial inflammation (inflammatory viral cardiomyopathy or viral myocarditis with cardiomegaly).

Purpose of the Study:

  • To define viral cardiomyopathy and its diagnostic criteria.
  • To identify common cardiotropic viruses associated with cardiac conditions.
  • To differentiate between viral cardiomyopathy and inflammatory viral cardiomyopathy.

Main Methods:

  • Diagnosis relies on endomyocardial biopsy adhering to WHO/WHF criteria.

Related Experiment Videos

  • Polymerase Chain Reaction (PCR) techniques are crucial for identifying viral genomes.
  • Distinguishing features include the presence or absence of myocardial inflammation (lymphocyte and macrophage counts).

    • Main Results:

    • The most frequently detected cardiotropic viruses include Parvovirus B19, enteroviruses, adenoviruses, and cytomegalovirus.
    • Epstein-Barr virus and influenza virus are less commonly identified.
    • Endomyocardial biopsy and PCR are essential for accurate diagnosis.

    Conclusions:

    • Viral cardiomyopathy is defined by viral persistence in a dilated heart.
    • Accurate diagnosis requires endomyocardial biopsy and PCR to detect viral genomes.
    • Understanding the specific cardiotropic viruses is key to managing these rare but serious cardiac conditions.