Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Retroviral vectors to study cell differentiation.

Takunori Satoh1, Donna M Fekete

  • 1Department of Biological Sciences, 1392 Lilly Hall of Science, Purdue University, West Lafayette, IN 47907-1392, USA.

Frontiers in Bioscience : a Journal and Virtual Library
|November 29, 2002
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Biotin methyl ester enhances cargo release in RUSH system and enables rapid biotinylation with TurboID.

Communications biology·2025
Same author

Studying Cargo Transport Using RudLOV.

Bio-protocol·2025
Same author

Lytic photoreceptor cell death caused by Rab escort protein deficiency in Drosophila.

FEBS letters·2025
Same author

Comprehensive study of SNAREs involved in the post-Golgi transport in <i>Drosophila</i> photoreceptors.

Frontiers in cell and developmental biology·2024
Same author

RudLOV is an optically synchronized cargo transport method revealing unexpected effects of dynasore.

EMBO reports·2024
Same author

Cell-wide arrangement of Golgi/RE units depends on the microtubule organization.

Cell structure and function·2024

Retroviral vectors enable gene transfer in dividing cells for developmental biology research. This review covers their use in gene expression and lineage analysis for studying cell differentiation in embryos.

Area of Science:

  • Developmental biology
  • Genetics
  • Clinical science

Background:

  • Retroviral vectors are key tools for gene transfer into dividing cells.
  • Their application spans in vitro and in vivo research settings.
  • Expanding use in developing biological systems.

Purpose of the Study:

  • To review the application of retroviral vectors in developmental biology.
  • Focus on ectopic gene expression and lineage analysis.
  • Investigate cell differentiation mechanisms in embryonic models.

Main Methods:

  • Gene transfer using retroviral vectors.
  • Ectopic gene expression induction.
  • Lineage tracing and analysis.
  • Studies in murine and chick embryos.

Related Experiment Videos

Main Results:

  • Retroviral vectors facilitate effective gene transfer for research.
  • Ectopic gene expression aids in studying gene function.
  • Lineage analysis reveals cell differentiation pathways.
  • Insights gained from murine and chick embryonic models.

Conclusions:

  • Retroviral vectors are versatile tools for studying cell differentiation.
  • Essential for understanding developmental processes in embryos.
  • Contribute significantly to genetics and clinical science.