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Related Experiment Videos

A comparison of ketamine and lidocaine spray with propofol for the insertion of laryngeal mask airway in children: a

Jae-Hyon Bahk1, Joohon Sung, In-Jin Jang

  • 1Department of Anesthesiology and Clinical Research Institute, Seoul National University Hospital, Seoul National University College of Medicine, Korea. bahkjh@plaza.snu.ac.kr

Anesthesia and Analgesia
|November 29, 2002
PubMed
Summary

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Ketamine and lidocaine spray provide safe laryngeal mask airway (LMA) insertion in children, maintaining spontaneous breathing. This combination avoids serious complications like apnea and airway obstruction often seen with propofol.

Area of Science:

  • Pediatric Anesthesiology
  • Airway Management
  • Pharmacology

Background:

  • The laryngeal mask airway (LMA) is a versatile device for ventilation and intubation.
  • Effective airway management in children requires maintaining spontaneous breathing.
  • Propofol and ketamine are common anesthetic agents, but their effects on LMA insertion vary.

Purpose of the Study:

  • To evaluate the efficacy and safety of ketamine and lidocaine spray versus propofol for laryngeal mask airway (LMA) insertion in children.
  • To determine if this combination can maintain spontaneous breathing during LMA placement.
  • To compare complication rates between ketamine/lidocaine and propofol groups.

Main Methods:

  • A double-blinded, randomized study involving 90 pediatric patients.

Related Experiment Videos

  • Patients received IV midazolam and glycopyrrolate premedication.
  • Two groups received either propofol or ketamine for anesthesia induction, with lidocaine spray used only in the ketamine group prior to LMA insertion.
  • Assessment of spontaneous respiration, airway obstruction, and other parameters post-LMA insertion.

    • Main Results:

    • Overall satisfactory or acceptable LMA insertion results were achieved in all patients only with ketamine doses of 3.0 or 3.5 mg/kg combined with lidocaine spray.
    • No propofol dose resulted in completely satisfactory outcomes, with frequent occurrences of apnea or airway obstruction.
    • Ketamine and lidocaine spray demonstrated appropriateness for LMA insertion, suggesting a safe method for managing difficult airways in children.

    Conclusions:

    • Ketamine combined with lidocaine spray is an appropriate and safe method for laryngeal mask airway (LMA) insertion in pediatric patients.
    • This anesthetic approach effectively avoids serious complications such as apnea and airway obstruction associated with propofol.
    • The ketamine and lidocaine spray combination facilitates LMA insertion while maintaining spontaneous breathing in children.