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Acrodermatitis enteropathica. Corneal involvement with histochemical and electron micrographic studies
Archives of Ophthalmology (Chicago, Ill. : 1960)
|March 1, 1975
Summary
A case study reports corneal changes in a patient with acrodermatitis enteropathica. Further research is needed to determine if these eye opacities are linked to the condition or its treatment.
Area of Science:
- Ophthalmology
- Dermatology
- Medical Histology
Background:
- Acrodermatitis enteropathica is a rare genetic disorder of zinc malabsorption.
- Corneal opacities can significantly impair vision and have various etiologies.
Purpose of the Study:
- To investigate the nature of corneal changes observed in a patient with acrodermatitis enteropathica.
- To determine the potential cause of linear subepithelial corneal opacities in this specific case.
Main Methods:
- Histochemical analysis of a corneal biopsy specimen.
- Electronmicrographic examination of the corneal lesion.
Main Results:
- The study identified linear subepithelial corneal opacities.
- Histochemical and electronmicrographic findings were inconclusive regarding the etiology.
Conclusions:
- The exact cause of the corneal opacities in this acrodermatitis enteropathica case remains undetermined.
- Further investigation is required to differentiate between the disease manifestation and potential drug-induced toxicity from iodochlorhydroxyquin therapy.