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A Luciferase-fluorescent Reporter Influenza Virus for Live Imaging and Quantification of Viral Infection
Published on: August 14, 2019
Insights
Annual influenza immunization is recommended for high-risk children 6 months and older. Increased efforts are needed to ensure these children and those aged 6-23 months, plus their contacts, receive the flu vaccine.
Area of Science:
- Pediatrics
- Immunology
- Public Health
Background:
- Children younger than 24 months and those with chronic conditions like asthma are hospitalized for influenza at rates similar to the elderly.
- Current recommendations focus on annual influenza immunization for high-risk children aged 6 months and older.
Purpose of the Study:
- To highlight the need for increased efforts in identifying and recalling high-risk children for influenza immunization.
- To encourage broader influenza immunization for children aged 6-23 months, their household contacts, and caregivers.
- To outline the ultimate goal of universal influenza immunization recommendations for children.
Main Methods:
- Review of epidemiologic studies on influenza hospitalization rates in children.
- Analysis of current influenza immunization recommendations for pediatric populations.
- Identification of barriers and considerations for expanding influenza immunization.
Main Results:
- Children with chronic conditions and those under 24 months face high rates of influenza-related hospitalizations.
- Current immunization strategies require enhancement to fully protect vulnerable pediatric groups.
- Feasible expansion of immunization to younger children and their contacts is encouraged.
Conclusions:
- Enhanced strategies are crucial for improving influenza vaccine uptake in at-risk and young children.
- Addressing physician and parent education, vaccine supply, and reimbursement are key to achieving universal childhood influenza immunization.
- The long-term objective is to establish routine influenza immunization for all healthy young children.
Abstract:
Epidemiologic studies indicate that children with certain chronic conditions, such as asthma, and otherwise healthy children younger than 24 months are hospitalized for influenza and its complications at high rates similar to those experienced by the elderly. Currently, annual influenza immunization is recommended for all children 6 months and older with high-risk conditions. To protect these children more fully against the complications of influenza, increased efforts are needed to identify and recall high-risk children for annual influenza immunization. In addition, immunization of children 6 through 23 months of age and their household contacts and out-of-home caregivers is now encouraged to the extent feasible. The ultimate goal is a universal recommendation for influenza immunization. Issues that need to be addressed before institution of routine immunization of healthy young children include education of physicians and parents about the morbidity caused by influenza, adequate vaccine supply, and appropriate reimbursement of practitioners for influenza immunization.
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