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Related Experiment Videos

[Screening for aneurysms in risk groups: meaningful?].

T Struffert1, W Reith

  • 1Klinik für bildgebende Diagnostik und Interventionen, Klinikum Saarbrücken, Germany. nreith@uniklinik-saarland.de

Der Radiologe
|November 30, 2002
PubMed
Summary
This summary is machine-generated.

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Screening for familial aneurysms is not recommended. However, adult dominant polycystic kidney disease patients with a family history of subarachnoid hemorrhage should undergo regular MRI angiography screening for intracranial aneurysms.

Area of Science:

  • Nephrology
  • Neurology
  • Radiology

Context:

  • Controversy exists regarding aneurysm screening in at-risk populations.
  • Current guidelines for aneurysm screening are lacking.
  • Screening for familial intracranial aneurysms is generally not advised.

Purpose:

  • To evaluate the necessity of screening for intracranial aneurysms in specific high-risk groups.
  • To determine optimal screening protocols for adult dominant polycystic kidney disease (ADPKD) patients with a history of subarachnoid hemorrhage (SAH).

Summary:

  • Adult dominant polycystic kidney disease (ADPKD) patients with a familial history of subarachnoid hemorrhage (SAH) exhibit a high prevalence (25%) of intracranial aneurysms.
  • Screening is recommended for this specific ADPKD subgroup due to the elevated risk.

Related Experiment Videos

  • Magnetic resonance angiography (MRA) is the suggested screening modality, performed every 2 to 3 years.

    • Impact:

    • This targeted screening approach aims to improve early detection and management of intracranial aneurysms in a high-prevalence ADPKD population.
    • Establishes a basis for future guideline development in specific aneurysm screening contexts.
    • Highlights the importance of personalized risk assessment in aneurysm screening strategies.