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[Analysis of the efficacy of lung-protective ventilation strategy in burn patients with respiratory dysfunction]
Liping Cao1, Gengxiang Liu, Shilin Deng
1Burn Institute of Tian Jin 300222, P.R. China.
Objective:
To investigate the efficacy of lung-protective ventilation strategy in burn patients with respiratory dysfunction.
Methods:
Mechanical ventilation was employed in 11 cases of severely burned patients with the pattern of synchronized intermittent mandatory ventilation and pressure support ventilation (SIMV + PSV). The tidal volume was set at 6 approximately 8 ml/kg and inspiratory plateau pressure was equal to or less than (
Results:
SIMV and PSV were applied in these patients for an average of 12.77 +/- 8.06 days. After treatment, the PaO(2)/FiO(2) ratio was obviously increased from 193.54 +/- 53.3 to 327.14 +/- 106.53 (P < 0.01). Furthermore, the PaCO(2) and pH values remained at normal range. Five out of 11 patients finally died, in which 3 were due to renal failure and one due to multiple organ dysfunction (MOD).
Conclusion:
Respiratory support in severely burned patients could be achieved by lung-protective ventilation strategy.