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Short bowel syndrome.
1Division of Digestive and Liver Diseases, University of Texas Southwestern Medical Center at Dallas, TX 75390-8887, USA.
Seminars in Gastrointestinal Disease
|December 5, 2002
Summary
Short bowel syndrome, a malabsorption condition from intestinal resection, requires careful management of nutrition and electrolytes. Some patients adapt and achieve oral independence, while others need lifelong parenteral nutrition or intestinal transplantation.
Area of Science:
- Gastroenterology
- Digestive System Disorders
Background:
- Short bowel syndrome (SBS) arises from extensive intestinal resection, leading to severe malabsorption.
- SBS presents significant challenges in managing nutritional, electrolyte, and water balance.
Observation:
- This report details the management of a typical SBS patient, addressing each malabsorption component.
- Patient outcomes vary, with some achieving oral intake independence through intestinal adaptation, while others require lifelong parenteral nutrition.
Findings:
- SBS patients face risks of gallstones, oxalate kidney stones, and d-lactic acidosis.
- The pathophysiology of these complications is outlined, alongside the current status of intestinal transplantation for irreversible cases.
Implications:
- Ongoing research into growth factors aims to stimulate intestinal growth and enhance absorptive capacity.
- These advancements may offer new therapeutic strategies for short bowel syndrome patients.