[Protease inhibitors as an anesthetic component in ENT surgery]

Both protease inhibitors and transamine should be included in anesthesiologic management of major traumatic operations in patients with initially impaired hemostasis to control inflammatory edema development after operation. As such drugs have an analgesic activity without effect on opiate structures, their different using in combination with narcotic analgesics provides multilevel control for pain conduction that elevates the quality of anesthesia.