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[Oral premedication in ambulatory surgical otorhinolaryngology in children]

I F Ostreĭkov, S A Pivovarov, V V Milenin

    Anesteziologiia I Reanimatologiia
    |December 5, 2002
    PubMed

    Insights

    Dormicum (midazolam) effectively premedicates children for ambulatory surgery without impacting cardiovascular function. Standard premedication, however, increases hemodynamic activity, particularly in older children.

    Area of Science:

    • Pediatric Anesthesiology
    • Cardiovascular Physiology
    • Pharmacology

    Context:

    • Ambulatory surgery in children requires effective premedication.
    • Assessing cardiovascular response to premedication is crucial.
    • Age-based grouping (4-7 and 8-14 years) was used.

    Purpose:

    • To compare the cardiovascular effects of Dormicum versus standard premedication in pediatric patients.
    • To evaluate the efficacy of Dormicum (0.5 mg/kg) in children undergoing otorhinolaryngology procedures.

    Summary:

    • Standard premedication activated central hemodynamics and enhanced left ventricular performance, especially in older children.
    • Dormicum (midazolam) at 0.5 mg/kg did not significantly alter central hemodynamics or left ventricular performance.
    • Dormicum induced moderate sympathetic activation, proving effective across all age groups.

    Impact:

    • Dormicum is a safe and effective premedication option for pediatric ambulatory surgery.
    • Findings support the use of Dormicum in pediatric otorhinolaryngology settings.
    • Provides insights into cardiovascular responses to different premedication strategies in children.

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