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Matrix-assisted Autologous Chondrocyte Transplantation for Remodeling and Repair of Chondral Defects in a Rabbit Model
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[Cartilage repair techniques--current status and potentials]

D Schäfer1

  • 1Orthopädische Universitätsklinik, Felix Platter-Spital Basel.

Praxis
|December 5, 2002
PubMed

Abstract:

A variety of cartilage repair techniques has been introduced into clinical application during the past 20 years. Tissue engineering is a technology which has the potential to treat these defects with low morbidity.

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Growth of Cartilage and Bone Tissue01:27

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Chondrocytes form a temporary cartilaginous model by dividing and secreting a thick gel-like extracellular matrix. Once the chondrocytes undergo programmed cell death, osteoblasts enter the site of the cartilaginous model. The process of replacing the temporary cartilaginous model with bone in an ordered manner is called endochondral ossification. In endochondral ossification, not all of the cartilage is replaced by bone tissue. Some cartilage that performs a protective and supportive function...

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