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Genetics of ankylosing spondylitis
M A Brown1, B P Wordsworth, J D Reveille
1Wellcome Trust Centre for Human Genetics, Spondyloarthritis and Bone Disease Research Group, Oxford, United Kingdom. mbrown@well.ox.ac.uk
Clinical and Experimental Rheumatology
|December 5, 2002
Abstract:
Ankylosing spondylitis is a common inflammatory rheumatic disease. Both susceptibility to and clinical manifestations of the disease are highly heritable. Although some genes, notably HLA-B27, have been implicated in susceptibility to the disease, the genetics of the condition are complex and many more genes involved in the condition await discovery.