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Updated: Aug 19, 2026

High-definition Fourier Transform Infrared (FT-IR) Spectroscopic Imaging of Human Tissue Sections towards Improving Pathology
Published on: January 21, 2015
[Determination of tissue optical parameters using HF modulation spectroscopy]
E Schleicher1, U Hampel, M J Silva
1Institut für Biomedizinische Technik, Technische Universität Dresden, Deutschland. eckhard.schleicher@mailbox.tu-dresden.de
Abstract:
Radio frequency modulation spectroscopy is a capable method to determine tissue optical parameters in-vivo. For the eventual purpose of clinical measurements we have developed and tested an rf laser spectroscopy device which enables a measurement of the spatial amplitude and phase shift profiles of backscattered modulated laser light. Spectral absorption and scattering coefficients are computed by inverse formulas derived from analytical solutions of the diffusion model of light transport in a semi-infinite geometry.

