Related Experiment Video
Updated: Aug 13, 2026

Production of Lentiviral Vectors for Transducing Cells from the Central Nervous System
Published on: May 24, 2012
Introduction to retroviruses and retroviral vectors
1Division of Hematology/Oncology, Department of Medicine, University of California-San Diego, La Jolla, California 92093, USA.
Abstract:
As various viral vector systems for gene transfer are developed, interest in using such systems in applied settings continues to grow. This Chapter is designed to provide background information for readers interested in learning about lentiviral vector systems for gene transfer applications but who lack a background in retrovirology. To assist those readers who are unfamiliar with retroviral vector systems, basic outlines of the retroviral replication cycle and of characteristics of retroviral vector systems are introduced here in order to present and define concepts and terms that are discussed in subsequent Chapters.
Related Concept Videos
Retrovirus Life Cycles
Retroviruses
Mechanisms of Retrovirus-induced Cancers
Mechanisms of Retrovirus-induced Cancers
Introduction to Virus
Size and Structure of Viral Genomes

