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Enantioselective synthesis of (-)-codeine and (-)-morphine

Barry M Trost1, Weiping Tang

  • 1Department of Chemistry, Stanford University, Stanford, California 94305-5080, USA. bmtrost@stanford.edu

Journal of the American Chemical Society
|December 6, 2002
PubMed
Summary

A novel synthetic strategy enables the efficient synthesis of opiate and amaryllidaceae alkaloids. This approach utilizes palladium-catalyzed reactions and visible light photochemistry to construct complex molecular architectures.

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