Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Functional MRI experiments: acquisition, analysis and interpretation of data.

N F Ramsey1, H Hoogduin, J M Jansma

  • 1Neuroscience Division, Department of Psychiatry, University Medical Center of Utrecht, Heidelberglaan 100, 3584 CX, Utrecht, The Netherlands.

European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology
|December 7, 2002
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

High-density electrocorticography reveals sensorimotor cortex engagement in two distinct sites with different roles during audiovisual, audio, and visual speech perception.

NeuroImage·2025
Same author

The effect of perceived auditory feedback on speech Brain-Computer Interface decoding performance.

Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology·2025
Same author

Don't put words in my mouth: Speech perception can generate False Positive activation of a speech BCI.

medRxiv : the preprint server for health sciences·2024
Same author

Neurotechnology in criminal justice: key points for neuroscientists and engineers.

Journal of neural engineering·2024
Same author

Reliability and validity of DTI-based indirect disconnection measures.

NeuroImage. Clinical·2023
Same author

The impact of etiology in lesion-symptom mapping - A direct comparison between tumor and stroke.

NeuroImage. Clinical·2023

Functional MRI (fMRI) research is advancing in data acquisition, processing, and analysis. Future developments aim to improve sensitivity for brain activity and design better tasks for neuroscience questions.

Area of Science:

  • Neuroscience
  • Medical Imaging

Background:

  • Functional MRI (fMRI) is a key tool for neuroscience research.
  • Ongoing developments focus on improving fMRI's sensitivity and task design.

Purpose of the Study:

  • To review strengths, weaknesses, and future directions in fMRI acquisition, processing, analysis, and interpretation.
  • To present a hypothesis-driven experiment on working memory practice and neural representation.

Main Methods:

  • Discusses blood oxygen level-dependent (BOLD) signal acquisition techniques, including parallel imaging and higher field scanners.
  • Covers data analysis methods like noise reduction, modeling cerebrovascular response, connectivity, and component analysis.
  • Highlights the importance of a priori hypothesis-driven experimental design.

Related Experiment Videos

Main Results:

  • fMRI results align with known functional topography despite complex BOLD signal mechanisms.
  • Technological advances like SENSE and 3T scanners are expected to enhance sensitivity.
  • Analytical algorithms aid in extracting meaningful information from fMRI data.

Conclusions:

  • Further sophistication in fMRI tasks and analysis will enable more complex neuroscience questions.
  • Hypothesis-driven experiments are crucial for targeted investigations, such as the working memory example provided.