Related Experiment Videos
Allogeneic haemopoietic stem cell transplantation for non-Hodgkin's lymphoma
Cynthia L Toze1, Michael J Barnett
1Leukemia/Bone Marrow Transplant Program of British Columbia, Division of Hematology, Vancouver Hospital and Health Sciences Centre, British Columbia Cancer Agency and University of British Columbia, Vancouver, British Columbia, Canada.
Abstract:
This chapter outlines the rationale for allogeneic haemopoietic stem cell transplantation in non-Hodgkin's lymphoma and pertinent results from published studies. Trials comparing allogeneic with autologous transplantation are discussed, as are disease-specific results for low-grade (including transformed), mantle cell and high-grade (Burkitt's and lymphoblastic) subtypes of the disease. Allogeneic transplantation for non-Hodgkin's lymphoma in the paediatric population, the use of unrelated donors, allografting after failed autologous or allogeneic transplantation, the graft-versus-lymphoma effect, the use of donor leukocyte infusions and non-myeloablative allografts are considered.