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Updated: Sep 28, 2026

Detection of Invasive Pulmonary Aspergillosis in Haematological Malignancy Patients by using Lateral-flow Technology
08:01

Detection of Invasive Pulmonary Aspergillosis in Haematological Malignancy Patients by using Lateral-flow Technology

Published on: March 22, 2012

Pathogenic molds (including Aspergillus species) in hospital water distribution systems: a 3-year prospective study

Elias J Anaissie1, Shawna L Stratton, M Cecilia Dignani

  • 1Myeloma Institute for Research and Treatment, University of Arkansas for Medical Sciences, Little Rock 72205, USA. elias114@aol.com

Blood
|December 7, 2002
PubMed

Insights

Hospital water systems may harbor molds, increasing infection risk for immunocompromised patients. This study found molds in 70% of water samples, suggesting water as a key source of airborne fungal spores in hospitals.

Area of Science:

  • Medical Mycology
  • Hospital Epidemiology
  • Infectious Diseases

Background:

  • Mold infections pose a significant threat to patients with hematologic malignancies.
  • Despite air filtration, mold infections are increasing, indicating other hospital sources.
  • Water systems are known reservoirs for pathogenic molds.

Purpose of the Study:

  • To investigate hospital water systems as a potential source of airborne molds in a bone marrow transplantation unit.
  • To determine the prevalence and characteristics of molds in various hospital environmental sources.

Main Methods:

  • Collected and analyzed samples from water, plumbing, environmental surfaces, and indoor air.
  • Utilized microscopic examination and mold culturing techniques.
  • Performed correlation and molecular analyses to link environmental and clinical mold strains.

Main Results:

  • Molds were recovered from 70% of water samples and 83% of indoor air samples.
  • Higher mold concentrations were found in bathrooms compared to patient rooms and hallways.
  • Strong correlations were observed between waterborne and airborne molds, suggesting aerosolization from water.

Conclusions:

  • Hospital water distribution systems can act as reservoirs for molds like Aspergillus.
  • Aerosolization of fungal spores from water poses a risk to vulnerable patients.
  • Enhanced water system monitoring and control are crucial for infection prevention.

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