Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Optimizing the dose of hormone replacement therapy.

Valerie Montgomery Rice1

  • 1Department of Obstetrics and Gynecology, University of Kansas Medical Center, Kansas City, Kansas 66160, USA.

International Journal of Fertility and Women'S Medicine
|December 10, 2002
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Plant Lectin, MoMo30, Pressures HIV-1 to Select for Variants with Deleted N-Linked Glycosylation Sites.

Viruses·2025
Same author

Scientific Hero: Dr. James E. K. Hildreth.

Journal of health care for the poor and underserved·2024
Same author

The Supreme Court Decision on Affirmative Action-Fewer Black Physicians and More Health Disparities for Minoritized Groups.

JAMA·2023
Same author

The Supreme Court and the Importance of Diversity in Medicine.

The New England journal of medicine·2023
Same author

Anti-human immunodeficiency virus-1 activity of MoMo30 protein isolated from the traditional African medicinal plant Momordica balsamina.

Virology journal·2023
Same author

Identification of a Novel Anti-HIV-1 Protein from <i>Momordica balsamina</i> Leaf Extract.

International journal of environmental research and public health·2022

New hormone replacement therapy (HRT) options offer various estrogen doses and delivery methods for menopause management. The focus is now on selecting progestogens that preserve estrogen

Area of Science:

  • Reproductive Endocrinology
  • Pharmacology
  • Women's Health

Background:

  • Hormone replacement therapy (HRT) has evolved significantly over the past 5 years.
  • Current HRT decisions involve selecting among various estrogen doses and delivery methods, including oral, transdermal, and intranasal options.
  • The addition of progestogen is standard for women with a uterus, but the choice of progestogen is debated regarding its impact on lipid profiles.

Purpose of the Study:

  • To review the current landscape of estrogen replacement therapy in menopause.
  • To discuss the evolving considerations in HRT, including dose, delivery, and progestogen selection.
  • To highlight the controversies surrounding long-term benefits of HRT for osteoporosis and cardiovascular disease prevention.

Main Methods:

Related Experiment Videos

  • Review of current literature and clinical practices regarding menopausal hormone therapy.
  • Analysis of different estrogen formulations, dosages, and administration routes (oral, transdermal, intranasal).
  • Discussion of the role and selection criteria for progestogens in HRT regimens.

    • Main Results:

    • A wide array of estrogen replacement options are now available, differing in dosage and delivery systems.
    • Estrogen therapy is effective for vasomotor symptoms and urogenital atrophy.
    • The long-term benefits of HRT for osteoporosis and cardiovascular disease prevention remain areas of ongoing research and debate, particularly concerning progestogen influence on lipid profiles.

    Conclusions:

    • The choice of HRT regimen requires careful consideration of estrogen dose, delivery method, and progestogen type.
    • While HRT benefits for symptom management are clear, its role in long-term disease prevention is still under review.
    • Further research is needed to determine optimal HRT strategies that maximize benefits while minimizing potential risks, especially concerning cardiovascular health.