Integrating experiential-phenomenological methods and neuroscience to study neural mechanisms of pain and consciousness
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Updated: Jul 21, 2026

Psychophysically-anchored, Robust Thresholding in Studying Pain-related Lateralization of Oscillatory Prestimulus Activity
Published on: January 21, 2017
Donald D Price1, James J Barrell, Pierre Rainville
1Department of Oral and Maxillofacial Surgery, Health Science Center, D8-44, University of Florida, PO Box 100416, 1600 Southwest Archer Rd, Gainesville, FL 32610-0416, USA. dprice@dental.ufl.edu
Abstract:
Understanding the nature of pain at least partly depends on recognizing its inherent first person epistemology and on using a first person experiential and third person experimental approach to study it. This approach may help to understand some of the neural mechanisms of pain and consciousness by integrating experiential-phenomenological methods with those of neuroscience. Examples that approximate this strategy include studies of second pain summation and its relationship to neural activities and brain imaging-psychophysical studies wherein sensory and affective qualities of pain are correlated with cerebral cortical activity. The experiential paradigm of offers the possibility of improved designs and methods for investigating neural mechanisms underlying pain and consciousness.
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