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Updated: Aug 11, 2026

Atomic Force Microscopy Imaging and Force Spectroscopy of Supported Lipid Bilayers
Published on: July 22, 2015
Lipid-lipid recognition in fluid bilayers: solving the cholesterol mystery
1Department of Chemistry, Lehigh University, Bethlehem, PA 18015, USA. slr0@lehigh.edu
Abstract:
Nearest-neighbour recognition measurements take 'molecular-level snapshots' of lipid organization in fluid bilayers by detecting and quantifying the thermodynamic tendency of two lipids to become nearest-neighbours. Recent nearest-neighbour recognition experiments have clarified the structural role that cholesterol plays in biological membranes. They have also clarified the influence that the linkage region of sphingolipids, the sugar head group of glycolipids, and lipid-peptide interactions have on lipid-lipid recognition.
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