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Related Experiment Videos

Severe scleritis and urticarial lesions.

Jennifer E Thorne1, Maria I Hernandez, Adrienne Rencic

  • 1Department of Ophthalmology, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA. jthorne@jhmi.edu

American Journal of Ophthalmology
|December 10, 2002
PubMed
Summary

This case report details the first instance of bilateral scleritis in hypocomplementemic urticarial vasculitis. Prompt treatment with corticosteroids and mycophenolate mofetil resolved ocular and skin symptoms.

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Area of Science:

  • Ophthalmology
  • Rheumatology
  • Immunology

Background:

  • Hypocomplementemic urticarial vasculitis (HUV) is a rare autoimmune disorder.
  • Ocular manifestations of HUV are uncommon but can be severe.

Observation:

  • A 67-year-old male presented with bilateral scleritis, rash, arthralgia, and malaise.
  • Diagnosis of hypocomplementemic urticarial vasculitis was confirmed through clinical and laboratory findings.

Findings:

  • The patient experienced resolution of scleritis and rash following treatment with high-dose oral corticosteroids and mycophenolate mofetil.
  • Bilateral scleritis was the presenting ocular manifestation in this HUV case.

Implications:

  • Ocular involvement, such as scleritis, can be an early indicator for diagnosing HUV.

Related Experiment Videos

  • This case highlights the importance of considering HUV in patients with unexplained scleritis and systemic symptoms.