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[Variants of left ventricular hypertrophy in patients on programmed hemodialysis]
Insights
Programmed hemodialysis (PHD) effectively treated chronic renal failure (CRF) in most patients. However, left ventricular hypertrophy progression during dialysis indicates a poor prognosis, particularly in older individuals.
Area of Science:
- Nephrology
- Cardiology
- Medical Technology
Context:
- Programmed hemodialysis (PHD) is a treatment for chronic renal failure (CRF).
- Cardiovascular complications are a major concern in CRF patients undergoing dialysis.
- Left ventricular hypertrophy (LVH) is a known cardiac adaptation in CRF.
Purpose:
- To identify objective prognostic indicators for cardiovascular function in CRF patients undergoing PHD.
- To compare the development of LVH in younger versus elderly CRF patients on PHD.
- To assess the impact of dialysis duration on LVH progression and prognosis.
Summary:
- PHD was successfully applied to 189 of 207 CRF patients over 10 years.
- LVH development was studied in young (18-40 years) and elderly (55-73 years) patient groups.
- Concentric LVH transitioned to eccentric or mixed forms with increased 'dialysis age', indicating a worse prognosis, especially in elderly patients.
Impact:
- The study highlights the prognostic significance of LVH progression in PHD patients.
- Findings suggest closer cardiovascular monitoring for CRF patients, particularly the elderly, undergoing long-term dialysis.
- Identifying unfavorable prognostic trends like LVH progression can help prevent fatal complications in CRF management.
Abstract:
Programmed hemodialysis (PHD) was successfully used in 189 of 207 patients with chronic renal failure (CRF) treated in Ulyanovsk Regional Hemodialysis Center for 10 years. To improve PHD results and prevent fatal complications, a search for objective prognostic indices of cardiovascular disease function was initiated. Left ventricular hypertrophy (LVH) development was compared in two groups of patients of different age (group 1--69 young patients aged 18-40 years; group 2--48 elderly patients aged 55-73 years. Concentric LVH transformed into excentric or mixed one in parallel to an increase of the patients' "dialysis age". This trend was prognostically unfavourable in both groups of patients especially in older patients.