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Updated: Jul 22, 2026

Methods for Cell-attached Capacitance Measurements in Mouse Adrenal Chromaffin Cell
Published on: October 22, 2014
PACAP activated adenylate cyclase in human sweat glands. An ultracytochemical study
M G Rambotti1, S Simonetti, A Spreca
1Sezione di Anatomia, Dipartimento di Medicina Sperimentale e Scienze Biochimiche, Universita di Perugia, C.P. 81, Succ. 3,06122 Perugia, Italy.
Abstract:
The ultracytochemical localization of adenylate cyclase (AC) was studied after stimulation with pituitary adenylate cyclase activating peptide (PACAP) in human sweat glands. PACAP stimulated AC in both eccrine and apocrine glands. In the secretory cells, enzymatic activity was associated with membranes involved in the secretory mechanism. In both glands, the cells of the excretory duct and myoepithelial cells presented AC activity. These localizations of enzymatic activity suggest a role for PACAP in regulating glandular secretion.
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