Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Corneal thickness in glaucoma.

E De Cevallos, C H Dohlman, W J Reinhart

    Annals of Ophthalmology
    |February 1, 1976
    PubMed
    Summary
    This summary is machine-generated.

    Central corneal stromal thickness increases in open-angle glaucoma and secondary glaucoma, likely due to endothelial dysfunction, not intraocular pressure. Angle closure glaucoma rarely causes permanent corneal damage.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Finding an Optimal Corneal Xenograft Using Comparative Analysis of Corneal Matrix Proteins Across Species.

    Scientific reports·2019
    Same author

    Cost effectiveness of the type II Boston keratoprosthesis.

    Eye (London, England)·2010
    Same author

    Neutrophil and eosinophil participation in atopic and vernal keratoconjunctivitis.

    Current eye research·2003
    Same author

    Histopathology of explanted collar button keratoprostheses: a clinicopathologic correlation.

    Cornea·2003
    Same author

    An unusual case of fungal keratitis: Metarrhizium anisopliae.

    Cornea·2001
    Same author

    Keratoprosthesis: an update.

    Current opinion in ophthalmology·2001
    Same journal

    Ocular toxicity of systemic chemotherapy with megadoses of carmustine and mitomycin.

    Annals of ophthalmology·1994
    Same journal

    Congenital intrastromal epithelial cyst of the iris.

    Annals of ophthalmology·1994
    Same journal

    Diagnosis and treatment of orbital hemorrhagic lesions.

    Annals of ophthalmology·1994
    Same journal

    Clinical features of toxoplasmic retinochoroiditis in patients with acquired immunodeficiency syndrome.

    Annals of ophthalmology·1994
    Same journal

    The closed chamber slipping suture technique for iris repair.

    Annals of ophthalmology·1994
    Same journal

    The effect of gravity on the amplitude of accommodation.

    Annals of ophthalmology·1994
    See all related articles

    Area of Science:

    • Ophthalmology
    • Glaucoma Research
    • Corneal Physiology

    Background:

    • Glaucoma encompasses various conditions affecting the optic nerve.
    • Corneal stromal thickness is a key ocular parameter.
    • Endothelial function plays a role in corneal health and intraocular pressure regulation.

    Purpose of the Study:

    • To compare central corneal stromal thickness (CCT) in glaucoma patients versus normal controls.
    • To investigate the relationship between CCT and glaucoma type, intraocular pressure, and treatment.

    Main Methods:

    • Measurement of central corneal stromal thickness in patients with open-angle glaucoma, secondary glaucoma, and acute angle closure glaucoma.
    • Comparison of CCT measurements with a control group of normal patients.

    Related Experiment Videos

    Main Results:

    • A small but significant increase in CCT was observed in open-angle glaucoma, attributed to endothelial dysfunction.
    • Secondary glaucoma cases showed markedly increased corneal thickness, likely due to endothelial damage.
    • No correlation was found between CCT and glaucoma duration or medication type.
    • Intraocular pressure level did not appear to be a significant factor in CCT changes.
    • Permanent corneal damage after acute angle closure glaucoma attacks was infrequent.

    Conclusions:

    • Endothelial dysfunction is a probable cause of increased corneal thickness in open-angle and secondary glaucoma.
    • Intraocular pressure is not the primary driver of stromal thickness changes in these glaucoma types.
    • Corneal integrity is generally preserved after acute angle closure glaucoma episodes.