Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Oesophageal disorders: future developments.

William Tam1, John Dent

  • 1Department of Gastroenterology, Hepatology and General Medicine, Royal Adelaide Hospital, Adelaide, Australia.

Best Practice & Research. Clinical Gastroenterology
|December 11, 2002
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A Digital Health Approach to Improve Compliance With Surveillance Colonoscopy Guidelines: The SCOPES Program: Study protocol for a stepped-wedge cluster trial.

Cancer medicine·2026
Same author

Impact of Hiatus Hernia and Reflux on Bolus Transport Through the Esophagus and the Esophagogastric Junction and in Relation to Dysphagia.

Neurogastroenterology and motility·2025
Same author

An Exploration of Wearable Device Features Used in UK Hospital Parkinson Disease Care: Scoping Review.

Journal of medical Internet research·2023
Same author

Transition-metal-catalyzed domino reactions of strained bicyclic alkenes.

Beilstein journal of organic chemistry·2023
Same author

Luminal Chemoreceptors and Intrinsic Nerves: Key Modulators of Digestive Motor Function.

Advances in experimental medicine and biology·2022
Same author

Erratum: Cold snare polypectomy of colorectal polyps ≤ 10 mm on clopidogrel: Australian and New Zealand randomized controlled trial.

Endoscopy international open·2022
Same journal

Needle-based confocal laser endomicroscopy and artificial intelligence in pancreatic cystic lesions: Insights and clinical advances.

Best practice & research. Clinical gastroenterology·2026
Same journal

Evidence-based approach to the diagnosis, management and surveillance of pancreatic cystic lesions: from the guidelines to the clinical practice.

Best practice & research. Clinical gastroenterology·2026
Same journal

Pancreatic cystic lesions in hereditary syndromes: Diagnostic role of endoscopic ultrasound.

Best practice & research. Clinical gastroenterology·2026
Same journal

Predictive risk models for the diagnosis and cancer progression of pancreatic cysts.

Best practice & research. Clinical gastroenterology·2026
Same journal

Preface.

Best practice & research. Clinical gastroenterology·2026
Same journal

Endoscopic ultrasound-guided treatment of pancreatic lesions.

Best practice & research. Clinical gastroenterology·2026
See all related articles

Diagnosing gastro-oesophageal reflux disease relies on symptoms, with potential improvements from advanced endoscopy. Future treatments may include new drugs and therapies, alongside strategies to manage Barrett's oesophagus and reduce cancer risk.

Area of Science:

  • Gastroenterology and Digestive Health
  • Oncology
  • Medical Diagnostics

Background:

  • Gastro-oesophageal reflux disease (GERD) diagnosis primarily relies on symptom patterns.
  • Short-segment Barrett's oesophagus is common, but its link to adenocarcinoma risk is unclear.
  • Current endoscopic surveillance for Barrett's oesophagus lacks definitive cost-effectiveness data.

Purpose of the Study:

  • To review diagnostic advancements and future therapeutic options for GERD.
  • To discuss the risk of adenocarcinoma in Barrett's oesophagus and potential biomarkers.
  • To evaluate the role of endoscopic surveillance and chemoprevention strategies.

Main Methods:

  • Literature review of diagnostic techniques, including high-resolution endoscopy and biopsy.

Related Experiment Videos

  • Analysis of emerging therapeutic strategies beyond proton pump inhibitors.
  • Examination of research on Barrett's oesophagus biomarkers, cytology, and chemoprevention.

    • Main Results:

    • Advanced endoscopy and biopsy can enhance GERD symptom pattern diagnosis.
    • Novel therapies like acid pump blockers and physical anti-reflux treatments are emerging.
    • Biomarkers and cytology show promise for stratifying Barrett's oesophagus cancer risk.
    • Ablation of Barrett's epithelium can reverse the condition, but long-term outcomes are uncertain.

    Conclusions:

    • GERD diagnosis and treatment are evolving with new technologies and therapies.
    • Further research is needed to clarify the adenocarcinoma risk associated with Barrett's oesophagus and optimize surveillance.
    • Chemoprevention and epithelial ablation represent potential future strategies for managing Barrett's oesophagus and its malignant transformation.