Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Serotonin syndrome].

P Lheureux1, A Penaloza, V De Cottenier

  • 1Service des Urgences, Unité de Toxicologie Aiguë, Hôpital Erasme, U.L.B.

Revue Medicale De Bruxelles
|December 12, 2002
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Carboxyhemoglobin half-life toxicokinetic profiles during and after normobaric oxygen therapy: On a swine model.

Toxicology reports·2024
Same author

A one-arm surgical trial of obstructive sleep apnea (OSA) patients before and 12 months after Bilateral Internal Ramus Distraction of the mandible (BIRD).

Sleep medicine·2021
Same author

[Posttraumatic stress disorder : Risk factors, phenomenology, early recognition and management].

Der Unfallchirurg·2020
Same author

Venous thromboembolism risk stratification for patients with lower limb trauma and cast or brace immobilization.

PloS one·2019
Same author

[Psychological care in the intensive care unit : Task areas, responsibilities, requirements, and infrastructure].

Medizinische Klinik, Intensivmedizin und Notfallmedizin·2018
Same author

Effect of Pressure Support Ventilation on Carboxyhemoglobin Toxicokinetic after Acute Carbon Monoxide Intoxication: a Swine Model.

Journal of medical toxicology : official journal of the American College of Medical Toxicology·2018
Same journal

[Breast cancer screening : a tool for informed decision making].

Revue medicale de Bruxelles·2018
Same journal

[Breast cancer screening : present situation and prospects].

Revue medicale de Bruxelles·2018
Same journal

[Guidelines in medical imaging : objectives, limits and radiation protection].

Revue medicale de Bruxelles·2018
Same journal

[How to avoid overmedicalization of the elderly patient ?]

Revue medicale de Bruxelles·2018
Same journal

[Ethical, pedagogical, socio-political and anthropological implications of quaternary prevention].

Revue medicale de Bruxelles·2018
Same journal

[New strategies in specific care for benign prostatic hypertrophy in older men].

Revue medicale de Bruxelles·2018
See all related articles

Serotonin syndrome, a dangerous condition from excess serotonin, presents with cognitive, neuromuscular, and autonomic symptoms. While supportive care is primary, 5-HT2 blockers like cyproheptadine may offer some treatment benefits.

Area of Science:

  • Pharmacology
  • Toxicology
  • Neurology

Context:

  • Serotonin syndrome arises from excessive intrasynaptic 5-hydroxytryptamine (serotonin).
  • It can be induced by psychotropic and non-psychiatric medications.
  • This condition poses significant health risks, potentially leading to fatality.

Purpose:

  • To describe the clinical manifestations and pathophysiology of serotonin syndrome.
  • To differentiate serotonin syndrome from neuroleptic malignant syndrome.
  • To review current and potential therapeutic strategies for serotonin syndrome.

Summary:

  • Serotonin syndrome is characterized by cognitive, neuromuscular, and autonomic dysfunction due to elevated serotonin levels.
  • Neuroleptic malignant syndrome is a key differential diagnosis.

Related Experiment Videos

  • While supportive treatment is standard, 5-HT2 receptor antagonists such as cyproheptadine show potential efficacy.

    • Impact:

    • Highlights the need for increased physician awareness to ensure prompt recognition and management.
    • Emphasizes the potential utility of specific pharmacological interventions.
    • Contributes to safer medication practices by underscoring drug interactions and toxicity risks.