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[Partial androgenic deficit in the aging male]
J Mockel1, C Schulman, J Sternon
1Service d'Endocrinologie, Hôpital Erasme.
Revue Medicale De Bruxelles
|December 12, 2002
Summary
Aging men may experience low testosterone (hypotestosteronemia). Androgen therapy, particularly testosterone gel, is discussed for benefits and risks. Sildenafil is favorable for erectile dysfunction if no contraindications exist.
Area of Science:
- Endocrinology
- Andrology
- Geriatrics
Background:
- Aging males can experience hypotestosteronemia, with testosterone levels below 3 ng/ml.
- Androgen deficiency in aging men requires careful consideration of treatment options.
Purpose of the Study:
- To discuss the indications for androgenic treatment in aging males.
- To evaluate the benefits, risks, and contraindications of various therapeutic molecules.
- To identify the preferred treatment for hypotestosteronemia and erectile dysfunction.
Main Methods:
- Review of current medical literature on testosterone replacement therapy.
- Analysis of clinical guidelines for androgenic treatments.
- Assessment of risk-benefit ratios for different therapeutic agents.
Main Results:
- Testosterone gel is emerging as a primary choice for treating hypotestosteronemia in aging men.
- Sildenafil demonstrates a favorable benefit/risk ratio for erectile dysfunction in men with normal testosterone levels, barring contraindications.
Conclusions:
- Androgen replacement therapy, especially with testosterone gel, offers a viable option for aging men with hypotestosteronemia.
- Sildenafil is a recommended treatment for erectile dysfunction in eugonadal men when appropriate.