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The pathogenesis of atopic eczema
1Dermatopharmacology Unit, University of Southampton, Southampton General Hospital, Southampton SO16 6YD.
Abstract:
Atopic eczema is associated with a genetic predisposition to dysregulation of the immune system. T lymphocytes differentiate towards the Th2 type with promotion of immunoglobulin E antibodies. Allergic responses to environmental allergens develop and microbes, including staphylococci and pityrosporum yeasts, may contribute to the inflammatory process.
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