Eyelid verrucous carcinoma
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Updated: Sep 28, 2026
Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia
Published on: August 9, 2024
J Monescillo1, E Mencía-Gutiérrez, E Gutiérrez-Díaz
1Department of Ohthalmology, 12 Octubre Hospital, Complutense University, Madrid, Spain.
Purpose:
To report a case of verrucous carcinoma (VC) that presented as an eyelid mass on the right eye.
Case Report:
A 66-year-old man developed a slow-growing eyelid lesion on the lateral canthus of the right eye. The tumor was firm, well-defined, sessile, acuminate, and exuded foul-smelling fluid.
Results:
Excisional biopsy revealed a VC. The patient remains asymptomatic.
Conclusions:
VCs are extremely rare eyelid tumors. This clinicopathological entity is a low-grade variant of squamous cell carcinoma that occurs mainly in the intraoral, genitogluteal, and plantar areas. A role of human papillomavirus (HPV) in these tumors has been recently identified. VCs characteristically show locally aggresive growth. This is the second case reported in the literature on the eyelid. VC should be considered in the differential diagnosis of eyelid tumors.
