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Related Experiment Videos

Fetal therapy.

Mark I Evans1, Michael R Harrison, Alan W Flake

  • 1Columbia University College of Physicians and Surgeons, St Luke's Roosevelt Hospital Center, 1000 10th Avenue, New York, NY 10019, USA.

Best Practice & Research. Clinical Obstetrics & Gynaecology
|December 12, 2002
PubMed
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Fetal therapies have advanced over 40 years, treating genetic and congenital anomalies before birth. Successful treatments now exist for various conditions, improving prenatal care.

Area of Science:

  • Medical Science
  • Genetics
  • Pediatrics

Background:

  • Fetal genetic and congenital anomalies pose significant health challenges.
  • Historically, treatment options for these conditions were limited.
  • Advances in medical technology have opened new avenues for prenatal interventions.

Purpose of the Study:

  • To review the evolution and scope of in utero treatments for fetal anomalies.
  • To highlight successful therapeutic interventions developed over the past four decades.
  • To underscore the growing possibilities in fetal medicine.

Main Methods:

  • Review of historical data and clinical outcomes of fetal therapies.
  • Analysis of surgical, pharmacological, and regenerative medicine approaches.

Related Experiment Videos

  • Compilation of successful case studies and treatment modalities.
  • Main Results:

    • Successful open procedures for congenital diaphragmatic hernia, lung malformations, and tumors.
    • Effective use of shunts for fetal uropathies and fluid collections.
    • Pharmacological treatments for congenital adrenal hyperplasia and neural tube defect prevention.
    • Emerging stem cell therapies for severe combined immunodeficiency disorder.

    Conclusions:

    • In utero treatment for a range of fetal anomalies has significantly advanced.
    • A diverse array of successful fetal therapies is now available.
    • Continued innovation promises further improvements in prenatal treatment options.