The effects of removal of sodium ions from the mucosal solution on sugar absorption by rabbit ileum

Net absorption and accumulation of D-galactose, beta-methyl D-glucose and low concentrations of 3-0-methyl-D-glucose by sheets of rabbit ileum are observed even when Na+ in the mucosal solution is replaced by choline. This indicates that active sugar transport can occur in the direction opposite to the brush-border Na+ gradient.