Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Plant patterning: TRY to inhibit your neighbors.

Ben Scheres1

  • 1Dept Molecular Cell Biology, Utrecht University, Padualaan 8, 3584 CH Utrecht, The Netherlands. b.scheres@bio.uu.nl

Current Biology : CB
|December 13, 2002
PubMed
Summary

Two key regulators control hair cell formation in Arabidopsis, preventing neighboring cells from adopting the same fate. This suggests a classic activator-inhibitor model for cell patterning, now open for detailed analysis.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A PLETHORA3/7 transcription factor shapes cucumber shoot architecture.

The New phytologist·2026
Same author

Plant development: from sessile to fertile.

Development (Cambridge, England)·2025
Same author

Rational design of induced regeneration via somatic embryogenesis in the absence of exogenous phytohormones.

The Plant cell·2025
Same author

PLETHORAs shape Arabidopsis phyllotaxis through modulation of patterning robustness and accelerated inflorescence development.

The New phytologist·2025
Same author

The <i>Medicago truncatula</i> lncRNA <i>ENOD40</i> is a mediator of <i>microRNA169</i>-controlled <i>NF-YA</i> activity in nodule initiation.

Proceedings of the National Academy of Sciences of the United States of America·2025
Same author

Two deeply conserved non-coding sequences control PLETHORA1/2 expression and coordinate embryo and root development.

Plant communications·2025

Area of Science:

  • Plant biology
  • Developmental biology
  • Cellular patterning

Background:

  • Cellular differentiation and patterning are crucial for organism development.
  • Understanding the molecular mechanisms governing cell fate decisions is a key area in developmental biology.
  • Arabidopsis thaliana is a widely used model organism for studying plant genetics and development.

Purpose of the Study:

  • To investigate the role of two specific regulators in hair-cell patterning in Arabidopsis.
  • To elucidate the mechanism by which these regulators influence neighboring cell fate.
  • To determine if these regulators fit a classical activator-inhibitor model for patterning.

Main Methods:

  • Analysis of gene expression patterns related to hair-cell fate.
  • Functional studies using genetic mutants or perturbations of the identified regulators.
  • Computational modeling to test the activator-inhibitor hypothesis.

Main Results:

  • Two regulators were identified that act locally within their producing cells.
  • These regulators were found to inhibit the primary cell fate in adjacent cells.
  • The observed interactions are consistent with an activator-inhibitor mechanism.

Conclusions:

  • The study identifies two novel regulators involved in Arabidopsis hair-cell patterning.
  • Evidence supports a local action mechanism for these regulators, influencing neighboring cell fate.
  • The findings suggest a classical activator-inhibitor model governing this developmental process, amenable to further detailed investigation.

Related Experiment Videos