Adverse reaction to surgical sutures in thyroid surgery
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Published on: July 28, 2026
Eitan Hocwald1, Jean-Yves Sichel, Ithak Dano
1Department of Otolaryngology/Head & Neck Surgery, Hadassch University Hospital, Jerusalem, Israel.
Background:
A mild reaction to surgical sutures after thyroid surgery is common and is characterized by local edema and inflammation around the surgical scar. Severe reaction with microabscesses and granulomatous masses is quite rare.
Methods And Results:
Two cases of severe reaction to silk sutures after thyroid surgery are presented. Meticulous surgical removal of all surgical sutures along with granulomatous masses, granulation tissue, and microabscesses cured both patients. Pathologic examination revealed giant cells and lymphocytes. Intradermal skin tests were positive to silk sutures. The etiology and the treatment options are discussed.
Conclusions:
In rare cases, severe reaction to silk sutures may develop after thyroid surgery. Surgical removal of the stitches is the treatment of choice. Intradermal skin test is a good predictor of allergy to sutures.
Insights
Severe reactions to silk sutures after thyroid surgery, though rare, can occur. Surgical removal of sutures and affected tissue is the recommended treatment, with skin tests predicting suture allergy.
Area of Science:
- Surgical Pathology
- Allergy and Immunology
Background:
- Mild reactions to surgical sutures post-thyroidectomy, including edema and inflammation, are common.
- Severe reactions, manifesting as microabscesses and granulomatous masses, are infrequent.
Observation:
- Two cases of severe reactions to silk sutures following thyroid surgery were documented.
- Patients presented with microabscesses and granulomatous masses requiring intervention.
Findings:
- Meticulous surgical excision of sutures, granulomatous masses, and granulation tissue led to patient recovery.
- Pathological examination revealed characteristic inflammatory infiltrates, including giant cells and lymphocytes.
- Intradermal skin tests confirmed a specific allergy to silk sutures in both cases.
Implications:
- Severe allergic reactions to silk sutures, while rare, necessitate prompt surgical intervention.
- Surgical suture removal is the primary treatment for severe suture reactions.
- Intradermal skin testing serves as a valuable diagnostic tool for identifying suture allergies.
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