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Synthetic applications of chiral 2,3-dihydro-4-pyridones
Sajan Joseph1, Daniel L Comins
1Eli Lilly & Company, Lilly Corporate Center Drop Code 0528, Indianapolis, IN 46285, USA. joseph_sajan@lilly.com
Abstract:
During the last decade, 2,3-dihydro-4-pyridones have become important intermediates for the synthesis of various alkaloids and biologically active compounds. The versatility of these heterocyclic building blocks has been demonstrated by the synthesis of several complex natural products. This review will cover recent work on the synthesis of substituted dihydropyridones, and their application in the synthesis of complex molecules.