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Related Concept Videos

Increased Body Temperature01:25

Increased Body Temperature

A body temperature above  38°C  (100.4 °F) is known as fever or pyrexia, and a person with fever is termed 'febrile.' Typically, the hypothalamus, a part of the brain that acts as the body's thermostat, regulates body temperature through a thermoregulatory setpoint. It receives signals from cold and warm thermal receptors throughout the body and adjusts the body's temperature accordingly. Fever occurs when this hypothalamic setpoint is altered, usually in response to an infection or illness.
Methods of reducing fever01:22

Methods of reducing fever

The signs and symptoms of fever include hot and dry skin, flushed face, thirst, muscle aches, anorexia, headache, tachycardia, tachypnea, and fatigue. Elevated body temperature is reduced using two methods: pharmacological and nonpharmacological. Proper identification and treatment of the root cause of a fever is of utmost importance.
Pharmacological Methods of Reducing Fever:
Decreased Body Temperature01:29

Decreased Body Temperature

A decreased body temperature can occur in patients with hypothermia and frostbite. Heat loss with extended cold exposure overpowers the body's ability to create heat, resulting in hypothermia. Core temperature readings help classify hypothermia. Mild hypothermia is temperatures between 32 °C (89.6 °F) and 35°C (95 °F) and is caused by impaired thermoregulation. Moderate hypothermia is temperatures between 28 C (82.4 °F) and 32 °C (89.6 °F) caused by sustained extreme cold exposure, and severe...
Types of Fever01:25

Types of Fever

Fever can be triggered by several factors, including infections, nervous system disorders, certain cancers, blood diseases like leukemia, embolism, thrombosis, heatstroke, dehydration, surgical trauma, crushing injuries, and allergic reactions.
Here are the different types of fever:
Veins01:17

Veins

Veins are an integral part of our circulatory system, serving as the blood vessels that transport blood from all body regions to the heart. They are a network of hollow tubes that carry blood low in oxygen from the body's cells back to the heart for reoxygenation. Veins are crucial for maintaining the body's overall fluid balance and the continuous circulation of blood.
Structure of Veins:
The structure of veins is specifically designed to assist in the low-pressure transportation of blood...
Homeostatic Imbalances in Body Temperature01:19

Homeostatic Imbalances in Body Temperature

Hyperthermia occurs when the body's temperature becomes unusually high, often due to heat exposure, intense physical activity, or certain illnesses. This condition can create a dangerous cycle where elevated body temperature increases the metabolic rate, generating more heat and potentially leading to organ failure and brain damage. A severe form of hyperthermia, called heat stroke, can raise body temperature to life-threatening levels. Fever, on the other hand, is a controlled form of...

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Related Experiment Video

Updated: Jul 6, 2026

Esophageal Heat Transfer for Patient Temperature Control and Targeted Temperature Management
06:43

Esophageal Heat Transfer for Patient Temperature Control and Targeted Temperature Management

Published on: November 21, 2017

Hot flushes.

Vered Stearns1, Lynda Ullmer, Juan F López

  • 1Breast Oncology Program, Department of Internal Medicine, University of Michigan Comprehensive Cancer Center, Georgetown, USA. cstearn1@jhmi.edu

Lancet (London, England)
|December 14, 2002
PubMed
Summary
This summary is machine-generated.

Hot flushes affect many individuals, but their cause is unclear. Selective serotonin reuptake inhibitors offer a safe and effective non-hormonal treatment, providing new insights into hot flush causes.

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Area of Science:

  • Reproductive endocrinology and neurobiology
  • Menopause and women's health research

Background:

  • Hot flushes are a common symptom affecting many women and some men.
  • The exact cause of hot flushes is currently unknown.
  • Hormonal decline may impact brain neurotransmitters and thermoregulation, leading to hot flushes.

Purpose of the Study:

  • To critically review current knowledge on the epidemiology, pathophysiology, and treatment of hot flushes.
  • To explore the effectiveness and implications of non-hormonal treatments for hot flushes.

Main Methods:

  • Literature review of epidemiological data.
  • Analysis of studies investigating the pathophysiology of hot flushes.
  • Assessment of treatment efficacy, including hormonal, non-pharmacological, and non-hormonal drug therapies.

Main Results:

  • Selective serotonin reuptake inhibitors (SSRIs) and related compounds demonstrate efficacy and safety in reducing hot flushes.
  • The effectiveness of SSRIs suggests a role for serotonergic pathways in hot flush generation.
  • Established hormonal treatments (oestrogens, progestagens) are effective but face patient and physician reluctance.

Conclusions:

  • Despite their prevalence, the pathophysiology of hot flushes requires further elucidation.
  • Non-hormonal treatments, particularly SSRIs, represent a promising therapeutic option.
  • Understanding the neurobiological underpinnings of hot flushes is crucial for developing better treatments.