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Calcinosis cutis universalis.

Z Ogretmen1, A Akay, C Bicakci

  • 1Department of Dermatology, Ataturk Training and Research Hospital, Izmir, Turkey.

Journal of the European Academy of Dermatology and Venereology : JEADV
|December 17, 2002
PubMed
Summary

This case study details idiopathic universal calcinosis cutis, a rare condition causing skin hardening due to subcutaneous calcifications. Diagnosis was confirmed via imaging and histology, highlighting unique patient presentation.

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Area of Science:

  • Dermatology
  • Radiology
  • Pathology

Background:

  • Idiopathic universal calcinosis cutis is a rare condition characterized by widespread subcutaneous calcification.
  • This report presents a case of a 49-year-old female with a 1.5-year history of skin hardening.

Observation:

  • Clinical presentation included skin hardening, mild anemia, elevated erythrocyte sedimentation rate, and normal rheumatological markers.
  • Laboratory findings revealed normal 24-hour urine calcium excretion but slightly low phosphate excretion.
  • Imaging studies, including ultrasound and mammography, demonstrated subcutaneous and reticular calcifications, respectively, while bone X-rays showed no abnormalities.

Findings:

  • Histological examination confirmed calcinosis cutis.
  • The diagnosis of idiopathic universal calcinosis cutis was established based on clinical, imaging, and histological findings.

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  • The case highlights the diagnostic process for this rare condition, emphasizing the utility of various imaging modalities.

    • Implications:

    • This case contributes to the understanding of idiopathic universal calcinosis cutis, a condition with limited reported cases.
    • The findings underscore the importance of integrating clinical, laboratory, and imaging data for accurate diagnosis.
    • Further research may elucidate the underlying mechanisms and potential therapeutic strategies for this rare disorder.