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Updated: Sep 28, 2026
08:10
Multi-enzyme Screening Using a High-throughput Genetic Enzyme Screening System
Published on: August 8, 2016
Screening for novel enzymes for biocatalytic processes: accessing the metagenome as a resource of novel functional
Patrick Lorenz1, Klaus Liebeton, Frank Niehaus
1BRAIN Aktiengesellschaft, Darmstaedter Strasse 34, D-64673, Zwingenberg, Germany. pl@brain.biotech.de
Current Opinion in Biotechnology
|December 17, 2002
Abstract:
Historically, biotechnology has missed up to 99% of existing microbial resources by using traditional screening techniques. Strategies of directly cloning 'environmental DNA' comprising the genetic blueprints of entire microbial consortia (the so-called 'metagenome') provide molecular sequence space that along with ingenious in vitro evolution technologies will act synergistically to bring a maximum of available sequence-space into biocatalytic application.
