Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Stretching single stranded DNA, a model polyelectrolyte.

M-N Dessinges1, B Maier, Y Zhang

  • 1Laboratoire de Physique Statistique de l'ENS, CNRS UMR 8550, associé aux Universités Paris VI et VII, 24 rue Lhomond, 75231 Paris Cedex 05, France.

Physical Review Letters
|December 18, 2002
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Search for Light Pseudoscalar Bosons, Pair-Produced in Higgs Boson Decays in the Four-Electron Final State in Proton-Proton Collisions at sqrt[s]=13  TeV.

Physical review letters·2026
Same author

First Evidence for Mixing-Induced CP Violation in B_{s}^{0}→J/ψϕ(1020) Decays in pp Collisions at sqrt[s]=13  TeV.

Physical review letters·2026
Same author

Observation of Suppressed Charged-Particle Production in Ultrarelativistic Oxygen-Oxygen Collisions.

Physical review letters·2026
Same author

Measurement of D^{0} Meson Photoproduction in Ultraperipheral Heavy Ion Collisions.

Physical review letters·2026
Same author

Observation of tWZ Production at the CMS Experiment.

Physical review letters·2026
Same author

First Exclusive Reconstruction of the B^{*+}, B^{*0}, and B_{s}^{*0} Mesons and Precise Measurement of Their Masses.

Physical review letters·2026
Same journal

Erratum: Spectroscopy and Ground-State Transfer of Ultracold Bosonic ^{39}K^{133}Cs Molecules [Phys. Rev. Lett. 135, 203401 (2025)].

Physical review letters·2026
Same journal

Erratum: Lifetime of the ^{2}F_{7/2} Level in Yb^{+} for Spontaneous Emission of Electric Octupole Radiation [Phys. Rev. Lett. 127, 213001 (2021)].

Physical review letters·2026
Same journal

Laser-Plasma Based Seeded Free Electron Laser in the High-Gain Regime.

Physical review letters·2026
Same journal

Parent Hamiltonians for Stabilizer Quantum Many-Body Scars.

Physical review letters·2026
Same journal

Properties of Heavy Cosmic Nuclei Phosphorus, Chlorine, Argon, Potassium, and Calcium: Results from the Alpha Magnetic Spectrometer.

Physical review letters·2026
Same journal

Role of Spin-Isospin Symmetries in Nuclear β-Decays.

Physical review letters·2026
See all related articles

Single stranded DNA (ssDNA) elastic properties align with models including base pairing and electrostatic repulsion. Suppressing base pairing reveals ssDNA as a polyelectrolyte model, deviating from ideal polymer behavior due to chain elasticity and electrostatic interactions.

Area of Science:

  • Biophysics
  • Polymer Physics
  • Molecular Biology

Background:

  • Single-stranded DNA (ssDNA) exhibits complex elastic properties influenced by its structure.
  • Understanding ssDNA elasticity is crucial for molecular mechanics and biophysics.
  • Existing models often simplify the interplay of base pairing and electrostatic forces.

Purpose of the Study:

  • To investigate the elastic properties of ssDNA under tension.
  • To model ssDNA behavior considering base pairing and electrostatic repulsion.
  • To use modified ssDNA as a model for generic polyelectrolytes.

Main Methods:

  • Mechanical pulling experiments on isolated ssDNA molecules.
  • Physicochemical treatment to suppress base pairing interactions.

Related Experiment Videos

  • Analysis of elastic behavior and comparison with theoretical models.

    • Main Results:

    • Experimental ssDNA elastic properties agree with models incorporating base pairing and screened electrostatic repulsion.
    • Altered ssDNA, lacking base pairing, serves as a polyelectrolyte model.
    • Deviations from ideal polymer behavior in altered ssDNA are attributed to chain elasticity and electrostatic self-avoiding interactions.

    Conclusions:

    • A comprehensive model accurately describes ssDNA elasticity, including structural and electrostatic factors.
    • Modified ssDNA provides insights into polyelectrolyte behavior.
    • Chain elasticity and electrostatic forces significantly influence ssDNA's mechanical response.