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[Multiple enchondromatosis: Ollier's disease].

W Schwarz1, J Hardes, M Schulte

  • 1Abteilung für Unfallchirurgie,Hand- und Wiederherstellungschirurgie, Universität Ulm. winfried.schwarz@extern.uni-ulm.de

Der Unfallchirurg
|December 18, 2002
PubMed
Summary

Ollier disease, a rare bone disorder, causes bone swelling and growth issues in children. Adults face a significant risk of malignant transformation, requiring surgical resection if it occurs.

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Area of Science:

  • Orthopedics
  • Oncology
  • Genetics

Background:

  • Ollier disease (multiple enchondromatosis) differs from solitary enchondroma.
  • It affects children with bone swelling and growth retardation.

Observation:

  • Adults with Ollier disease have a 40% risk of malignant transformation.
  • Clinical signs include pain, tumor growth, and cortical thinning.
  • Radiological signs indicate transformation to low-grade chondrosarcoma.

Findings:

  • Regular radiological screening is not necessary.
  • Surgical resection is indicated for malignant transformation.

Implications:

  • Early recognition of malignant signs is crucial for timely intervention.
  • Surgical management (marginal or wide resection) is the standard treatment for chondrosarcoma in Ollier disease.

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