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Combined Near-infrared Fluorescent Imaging and Micro-computed Tomography for Directly Visualizing Cerebral Thromboemboli
Published on: September 25, 2016
Diagnostic imaging for intracerebral hemorrhage
1Diagnostic Radiology, Cleveland Clinic Foundation, 9500 Euclid Avenue, L10, Cleveland, OH 44195, USA. aygunn@ccf.org
Abstract:
Magnetic resonance imaging (MRI) is an excellent tool for the diagnosis and evaluation of intracerebral hemorrhage with its unique specificity to hemoglobin degradation products in different stages. Computed tomography (CT) remains the diagnostic test of choice in the setting of acute intracerebral hemorrhage because of its exquisite sensitivity and specificity for small amounts of intracerebral hemorrhage (although there is emerging evidence that MRI may be as sensitive as CT). The effects of the biochemical evolution of intracerebral hemorrhage on the temporal MRI signal changes are described. This article discusses imaging features of the common causes of intracerebral hemorrhage.
Insights
Magnetic resonance imaging (MRI) offers unique insights into intracerebral hemorrhage by detecting hemoglobin byproducts. This review details MRI
Area of Science:
- Neuroradiology
- Neuroimaging
- Biomedical Engineering
Background:
- Intracerebral hemorrhage (ICH) diagnosis relies heavily on neuroimaging.
- Computed tomography (CT) is the current gold standard for acute ICH detection.
- Magnetic resonance imaging (MRI) shows promise due to its specificity for hemoglobin.
Purpose of the Study:
- To describe the temporal MRI signal changes related to the biochemical evolution of ICH.
- To discuss the imaging features of common causes of intracerebral hemorrhage.
- To highlight MRI's role in evaluating ICH.
Main Methods:
- Review of the literature on MRI characteristics of intracerebral hemorrhage.
- Analysis of temporal signal changes based on hemoglobin degradation products.
- Discussion of imaging findings for various etiologies of ICH.
Main Results:
- MRI exhibits unique specificity to hemoglobin degradation products, varying with hemorrhage stage.
- Temporal MRI signal changes correlate with the biochemical evolution of intracerebral hemorrhage.
- Emerging evidence suggests MRI may achieve sensitivity comparable to CT in acute ICH.
Conclusions:
- MRI is a valuable tool for diagnosing and evaluating intracerebral hemorrhage.
- Understanding temporal MRI signal changes aids in characterizing ICH.
- MRI provides comprehensive evaluation of ICH, including its underlying causes.
