Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Prostate cancer gene therapy.

Mitchell S Steiner1, Jeffrey R Gingrich, Ravi D Chauhan

  • 1Department of Urology, University of Tennessee Memphis, 1211 Union Avenue, Suite 340, Memphis, TN 38104, USA. msteiner@utmem.edu

Surgical Oncology Clinics of North America
|December 19, 2002
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Impact of Genomic Classifiers on Risk Stratification and Treatment Intensity in Patients With Localized Prostate Cancer : A Systematic Review.

Annals of internal medicine·2025
Same author

Genomic classifiers and prognosis of localized prostate cancer: a systematic review.

Prostate cancer and prostatic diseases·2024
Same author

Impact of Race on Outcomes of High-Risk Patients With Prostate Cancer Treated With Moderately Hypofractionated Radiotherapy in an Equal Access Setting.

Federal practitioner : for the health care professionals of the VA, DoD, and PHS·2022
Same author

A Phase Ib/II Study of Sabizabulin, a Novel Oral Cytoskeleton Disruptor, in Men with Metastatic Castration-resistant Prostate Cancer with Progression on an Androgen Receptor-targeting Agent.

Clinical cancer research : an official journal of the American Association for Cancer Research·2022
Same author

The impact of the social construct of race on outcomes among bacille Calmette-Guérin-treated patients with high-risk non-muscle-invasive bladder cancer in an equal-access setting.

Cancer·2021
Same author

Associations Between Female Sex and Treatment Patterns and Outcomes for Muscle-invasive Bladder Cancer.

Urology·2020

Gene therapy for prostate cancer shows promise, with ongoing trials evaluating its safety and effectiveness. Early results indicate it is well-tolerated, paving the way for further research in treating advanced and metastatic prostate cancer.

Area of Science:

  • Oncology
  • Molecular Biology
  • Gene Therapy

Background:

  • Prostate cancer remains a significant health concern, particularly in its advanced and metastatic stages.
  • Current treatment options have limitations, driving the need for novel therapeutic strategies.
  • Gene therapy offers a potential new avenue for treating prostate cancer.

Purpose of the Study:

  • To review the current status of gene therapy trials for prostate cancer.
  • To assess the safety and tolerability of gene therapy in prostate cancer patients.
  • To discuss the potential role of gene therapy in combination with conventional treatments.

Main Methods:

  • Review of ongoing gene therapy clinical trials globally.
  • Analysis of safety and tolerability data from early-phase studies.

Related Experiment Videos

  • Exploration of vector technologies and molecular pathway research.
  • Main Results:

    • Multiple gene therapy strategies are under investigation worldwide for prostate cancer.
    • Early clinical trials suggest that prostate gene therapy is safe and well-tolerated.
    • Advances in vector technology are supporting the development of gene therapy approaches.

    Conclusions:

    • Gene therapy is a developing treatment modality for prostate cancer.
    • Further clinical trials are necessary to determine the ultimate safety and efficacy of gene therapy, alone or in combination therapies.
    • Understanding prostate cancer's molecular pathways is crucial for advancing gene therapy effectiveness.