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Updated: Aug 14, 2026

Neuro-rehabilitation Approach for Sudden Sensorineural Hearing Loss
Published on: January 26, 2016
Etiology of syndromic and nonsyndromic sensorineural hearing loss
Nicolas Gürtler1, Anil K Lalwani
1Laboratory of Molecular Otology, Epstein Laboratories, Department of Otolaryngology-Head and Neck Surgery, University of California San Francisco, 533 Parnassus Avenue/Room U490A, San Francisco, CA 94143-0526, USA.
Abstract:
The past 10 years have seen an explosive gain in our understanding of molecular mechanisms of hearing and deafness. This has already resulted in improved diagnosis for the population with hereditary hearing loss. For syndromic hearing loss, we will see a shift from the historical terminology to a more precise genetic definition based on specific genetic abnormality. Functional studies of nonsyndromic deafness genes will elucidate the complex functional and hemostatic mechanisms in the inner ear. Ultimately, availability of gene therapy for the affected patients will bring to closure the circle of detection, identification, and correction of the disease.
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