Cost estimation of thyroid disorders in Germany

Area of Science:

• Endocrinology
• Public Health
• Health Economics

Background:

• Thyroid disorders represent a significant public health concern in Germany, with endemic goiter being the most prevalent.
• Economic impacts of thyroid morbidity necessitate a comprehensive assessment for effective healthcare planning.
• Existing data gaps hinder a full economic evaluation of autoimmune and malignant thyroid diseases.

Purpose of the Study:

• To assess the economic effects of thyroid disorder-related morbidity in Germany.
• To evaluate the cost-effectiveness of iodine supplementation for endemic goiter prevention.
• To analyze the economic consequences of recent radiation protection regulations on thyroid therapy.

Main Methods:

• A systematic review of national and international literature from 1981-2001.
• Analysis of data from insurance companies, public health departments, and federal statistics office.
• Examination of hospitalization length and costs associated with radioiodine therapy.

Main Results:

• Endemic iodine-deficiency goiter incurs annual costs of approximately 1 billion Euros.
• Iodine supplementation is expected to reduce goiter prevalence from 30%-40% to under 10%.
• New radiation protection regulations shortened hospitalization for radioiodine therapy, with median costs of 1,856 Euros (university) and 1,530 Euros (non-university).

Conclusions:

• Preventing iodine deficiency is crucial for reducing the direct and indirect economic costs of endemic goiter.
• Sustainable elimination of iodine deficiency requires ongoing commitment and support.
• Further research is needed for a comprehensive economic assessment of other thyroid conditions.