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[Evaluation of myometrial invasion in endometrial carcinoma]
Ping Peng1, Keng Shen, Jinghe Lang
1Department of Obstetrics and Gynecology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Science, Beijing 100730, China.
Objective:
To determine the value of preoperative ultrasound, intraoperative gross visual inspection and postoperative bulk specimen measurement in evaluating the diagnosis of myometrial invasion in endometrial carcinoma.
Methods:
A total of 133 cases of women with endometrial carcinoma were analyzed focusing on evaluating the diagnosis of myometrial invasion by preoperative ultrasound, intraoperative gross visual inspection and postoperative bulk specimen measurement. The relationship between CA(125) and endometrial carcinoma of 91 cases of endometrial carcinoma was also analyzed.
Results:
In the diagnosis of myometrial invasion and deep myometrial invasion, ultrasound showed a sensitivity of 62.6% and 47.8% and a specificity of 67.7% and 90.0%, respectively, and intraoperative gross visual inspection showed a sensitivity of 59.6% and 73.9% and a specificity of 76.5% and 94.6%, respectively. The sensitivity of postoperative bulk specimen measurement was 70.0% and 94.4% and the specificity was 92.0% and 97.7%, respectively. The levels of CA(125) had no correlation with depth of myometrial invasion in endometrial carcinoma, but they had correlation with International Federation of Gynecology and Obstetrics (FIGO) stage.
Conclusions:
Preoperative ultrasound, intraoperative gross visual inspection and postoperative bulk specimen measurement were helpful to the diagnosis of depth of myometrial invasion in endometrial carcinoma, and postoperative bulk specimen measurement seems to be better. CA(125) could not evaluate depth of myometrial invasion in endometrial carcinoma.