[Synthesis of some aminoacyl-AH-sepharoses via the N-carboxyanhydride method (author's transl)]
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Abstract:
(Aminoacyl)n=1-10-AH-Sepharoses can easily be prepared by the N-carboxy anhydride method from amino acid N-carboxy anhydrides and AH-Sepharose 4B at pH 10.2, 0degreesC in aqueous borate buffer. Syntheses of cystinyl-, cysteinyl-, isoleucyl-, leucyl- and phenylalanyl-AH-Sepharoses are described. An improved preparation for cystine bis(N-carboxy anhydride) is presented.