Tensor diffusion imaging in B12 leukoencephalopathy
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Updated: Sep 28, 2026
Diffusion Tensor Magnetic Resonance Imaging in the Analysis of Neurodegenerative Diseases
Published on: July 28, 2013
Susan M Kealey1, James M Provenzale
1Department of Radiology, Duke University Medical Center, Box 3808, Rm. 1533, Erwin Road, Durham, NC 27710-3808, USA. susankealey@hotmail.com
Abstract:
Anisotropy measurements were obtained from periventricular foci of T2 prolongation and adjacent normal-appearing white matter in a case of B12 leukoencephalopathy. Measurements were compared with mean values from two age-matched control subjects. Anisotropy was greatly reduced in the lesions evident on T2-weighted images and in the normal-appearing adjacent white matter (WM), indicating that the extent of WM tract disruption was greater than could be identified on routine MR sequences.
